Type 1 Diabetes Research

A Step Into Freedom From T1DM

About Me

Hello

I amShivani Desai

Type 1 diabetes researcher and enthusiast

Welcome to T1DM.org! It is a platform which consolidates my work about type 1 diabetes (T1DM) and its management. This forum invites an open interaction from national and international experts to manage type 1 diabetes, share their knowledge and collaborate to work towards freedom from this painful disease.

This forum includes the papers published by the author in the journals of repute. These papers primarily involve the content related to the etiology and pathophysiology of T1DM, the application of mesenchymal stem cells to manage T1DM and improve the quality of life in patients, and the correlation of diabetes with hepatic dysfunctions. It also includes papers related to the immunological aspects in the journey to prevent and reverse the disease.

With more interaction and collaborations, we can bring an end to T1DM and give a better life to the children who are at risk to develop this immensely agonising disease.

My Profile Contact Me

2 Patents

Diabetec foot ulcer (DFU) treatment using stem cell, Wound healing

26 Publications

T1DM vaccine research, Regenerative medicine research, 15 under process

10 Awards

'Woman Innovator' National Award 2022 and others, for research in T1DM

Journey So Far

2016

July

Inception of Idea

Development of vaccine to prevent and reverse type 1 diabetes mellitus

2018

September

t1dm.org Launched

Platform launched to consolidate research work about type 1 diabetes and its management

t1dm.org invites an open interaction from national and international experts to manage type 1 diabetes, share their knowledge and collaborate to work towards freedom from this painful disease

2020

June

Research Publication

First review paper on type 1 diabetes mellitus “Mapping of type 1 diabetes mellitus” published in Current Diabetes Reviews

2021

December

Preclinical Model Development

Preclinical model development project using Swiss albino mice started to study type 1 diabetes

2022

April

Phase 1 Preclinical Study

Stability test for vaccine formula conducted
Allergy test and safety study for vaccine formula conducted
Efficacy study of vaccine formula to prevent and reverse type 1 diabetes mellitus

My Latest Publications

Showing posts with label prevention. Show all posts
Showing posts with label prevention. Show all posts

[Review Paper] Is Type 1 Diabetes Preventable: Population Perspective


Survey Objective: Type 1 diabetes mellitus (T1DM) is growing in incidence over a few years. The objective of this short survey is to report the viewpoint of the general population about their belief if type 1 diabetes mellitus (T1DM) can be prevented. This will further motivate the researchers to accelerate their research to develop vaccines for the prevention and reversal of T1DM.

Methods: A survey was put up on LinkedIn asking a single question “Type 1 diabetes is preventable: Agree or disagree”. The poll was kept open for a period of two weeks and 220 votes were obtained from people belonging to the healthcare sector (n=168) as well as other professions (n=52).

Results: Out of 220 votes, 64% of people agree that T1DM is preventable and the remaining 36% disagree.

Conclusions: Results indicate that majority of people think that T1DM is preventable. Though there is no preventive vaccine at present, there is a hope to formulate such a vaccine that can prevent this autoimmune diabetes.

Journal: High Technology Letters

Keywords: Type 1 diabetes mellitus, Prevention, Perspective, Survey

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[Review Paper] Mapping Of Type 1 Diabetes Mellitus


Abstract: Type 1 diabetes mellitus (T1DM), an autoimmune disorder, is becoming widespread with approximately 97,700 children in India and 490,000 children worldwide affected. There are various etiological factors contributing to the expansion of its incidence in different geographical locations. Hence, the articles published in reputed journals were studies and data was collected for analyzing the aetiology and prevention of T1DM. It has been observed that hybrid insulin peptides act as key antigens for the autoreactive T cells and causes loss of self-tolerance in humans. The association of coxsackievirus B has been observed with the onset of T1DM. Accurate identification of the trigger can lead to the development of appropriate preventive measures. It can become a base for advanced studies to prevent T1DM in humans. This review will highlight the causes and some preventive actions which can be considered to eliminate T1DM.

Journal: Current Diabetes Reviews

Keywords: Type 1 diabetes mellitus; coxsackievirus B virus; etiology; pathogenesis; prevention

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SHIVANI DESAI
+91-20-4930-0148
Pune, India