A FORUM TO

TYPE 1 DIABETES MELLITUS

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A Step Into Freedom From Type 1 Diabetes

T1DM.org

T1DM.org is a platform which consolidates the author’s work about type 1 diabetes and its management. This forum invites an open interaction from national and international experts to manage type 1 diabetes, share their knowledge and collaborate to work towards freedom from this painful disease.

This forum only includes the papers published by the author in the journals of repute at the moment. These papers primarily involve the content related to the etiology and pathophysiology of T1DM, application of mesenchymal stem cells to manage T1DM and improve the quality of life in patients, and about the correlation of diabetes with hepatic dysfunctions. However, it will soon come up with the papers related to the immunomodulatory aspects in the journey to prevent and reverse the disease.

With more interaction and collaborations, we can bring an end to T1DM and give a better life to the children who are at risk to develop this immensely agonising disease.

Contact Us Publications

OUR APPROACH

1. In-vitro Study

Test the immunological reactions

2. Preclinical Study

Test the immunological responses in animal model

3. Formulation

Prepare a potential formulation candidate based on results and tests in in-vivo

4. Clinical Study

Clinical evaluation of the potential formation for T1DM
OUR T1DM PUBLICATIONS
All Research Articles Review Articles Videos
Showing posts with label etiology. Show all posts
Showing posts with label etiology. Show all posts

[Review Paper] A Peripheral Concept On Aetiology Of Type 1 Diabetes Mellitus

Abstract: Diabetes mellitus is a common metabolic disorder affecting a wide range of population worldwide. There are many types of diabetes mellitus, one of which is type 1 diabetes mellitus (T1DM). It is an autoimmune disorder caused in about 97,700 children in India and 490,000 children globally. Many etiological factors contribute to this disease. This review article is a collage of etiological factors causing T1DM. A better understanding of the aetiology is significant for prevention and management of the disease.


Journal: Pharmaceutical Resonance 

Keywords: Type 1 Diabetes Mellitus; Etiology; Autoantibodies; Extracellular matrix; Coxsackievirus B virus

[Review Paper] Mapping Of Type 1 Diabetes Mellitus

Abstract: Type 1 diabetes mellitus (T1DM), an autoimmune disorder, is becoming widespread with approximately 97,700 children in India and 490,000 children worldwide affected. There are various etiological factors contributing to the expansion of its incidence in different geographical locations. Hence, the articles published in reputed journals were studies and data was collected for analyzing etiology and prevention of T1DM. It has been observed that hybrid insulin peptides act as key antigens for the autoreactive T cells and causes loss of self-tolerance in humans. The association of coxsackievirus B has been observed with the onset of T1DM. Accurate identification of the trigger can lead to the development of appropriate preventive measures. It can become a base for advance studies to prevent T1DM in humans. This review will highlight the causes and some preventive actions which can be considered to eliminate T1DM.


Journal: Current Diabetes Reviews

Keywords: Type 1 diabetes mellitus; coxsackievirus B virus; etiology; pathogenesis; prevention

Read Full Review Paper

Type 1 Diabetes Mellitus: Aetiology And Pathogenesis

T1DM is allied with the selective destruction of insulin-producing β-cells in the pancreas. The commencement of clinical disease signifies the end stage of β-cell destruction which leads to T1DM. There is marked heterogeneity of the pancreatic lesions, which makes it difficult to follow the pathogenesis of selective β-cell destruction within the islet in T1DM1.

TESTIMONIALS

Dr. Shivani Desai is a thorough professional with strong Ethics. She has a keen interest in the field of Diabetes and also possesses an elaborate knowledge of Pre-clinical and Clinical Research.

Dr. Shivani Desai is passionate towards work and is an invaluable asset to any Institution or organization. I wish her all the success in personal and professional life.

Dr Hitt Sharma

TESTIMONIALS

Dr Shivani Desai is a hardcore researcher. Research is her birthright as she is born on National Science Day (28 Feb). She is passionate and deeply involved in Diabetes Research. She wishes to devote her entire career to converting Diabetes "Type 1 to Type None" following the slogan of JDRF.

Dr Ramesh Bhonde

TESTIMONIALS

Dr. Shivani Desai is self-motivated, perceptive, a sharp individual and takes that extra effort to achieve her goal. Her openness to feedback means she’s always learning and growing as a learner, an impressive strength that will continue to serve her well in her professional career and beyond. Rarely do you come across someone who is talented at both big picture ideas and executing the small details — Shivani is just that person.

Dr Hitt Sharma

TESTIMONIALS

Dr Shivani Desai plans to develop a poly vaccine for the prevention and better control of Type 1 diabetes. I am very much impressed by her keen interest to learn new aspects of diabetes. Her research zeal is evident from her recent publications in a span of one year.

Dr Ramesh Bhonde
Contact Us
Dr Shivani Desai
+91-20-49300148
Pune, India